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Structural basis for acyl-group discrimination by human Gcn5L2
Gcn5 is a conserved acetyltransferase that regulates transcription by acetylating the N-terminal tails of histones. Motivated by recent studies identifying a chemically diverse array of lysine acyl modifications in vivo, the acyl-chain specificity of the acetyltransferase human Gcn5 (Gcn5L2) was exa...
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| Publicat a: | Acta Crystallogr D Struct Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932917/ https://ncbi.nlm.nih.gov/pubmed/27377381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316007907 |
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