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Structural basis for acyl-group discrimination by human Gcn5L2

Gcn5 is a conserved acetyltransferase that regulates transcription by acetylating the N-terminal tails of histones. Motivated by recent studies identifying a chemically diverse array of lysine acyl modifications in vivo, the acyl-chain specificity of the acetyltransferase human Gcn5 (Gcn5L2) was exa...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Ringel, Alison E., Wolberger, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932917/
https://ncbi.nlm.nih.gov/pubmed/27377381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316007907
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