The Bromodomain of Gcn5 Regulates Site Specificity of Lysine Acetylation on Histone H3

In yeast, the conserved histone acetyltransferase (HAT) Gcn5 associates with Ada2 and Ada3 to form the catalytic module of the ADA and SAGA transcriptional coactivator complexes. Gcn5 also contains an acetyl-lysine binding bromodomain that has been implicated in regulating nucleosomal acetylation in...

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Publicat a:Mol Cell Proteomics
Autors principals: Cieniewicz, Anne M., Moreland, Linley, Ringel, Alison E., Mackintosh, Samuel G., Raman, Ana, Gilbert, Tonya M., Wolberger, Cynthia, Tackett, Alan J., Taverna, Sean D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
Matèries:
Special Issue Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223480/
https://ncbi.nlm.nih.gov/pubmed/25106422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.038174
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