The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p

The bromodomain is an ∼110 amino acid module found in histone acetyltransferases and the ATPase component of certain nucleosome remodelling complexes. We report the crystal structure at 1.9 Å resolution of the Saccharomyces cerevisiae Gcn5p bromodomain complexed with a peptide corresponding to resid...

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Detalhes bibliográficos
Main Authors: Owen, David J., Ornaghi, Prisca, Yang, Ji-Chun, Lowe, Nicholas, Evans, Philip R., Ballario, Paola, Neuhaus, David, Filetici, Patrizia, Travers, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305837/
https://ncbi.nlm.nih.gov/pubmed/11080160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6141
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