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Nucleosome competition reveals processive acetylation by the SAGA HAT module

The Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex hyperacetylates histone tails in vivo in a manner that depends upon histone 3 lysine 4 trimethylation (H3K4me3), a histone mark enriched at promoters of actively transcribed genes. SAGA contains a separable subcomplex known as the histone...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ringel, Alison E., Cieniewicz, Anne M., Taverna, Sean D., Wolberger, Cynthia
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603478/
https://ncbi.nlm.nih.gov/pubmed/26401015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508449112
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