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A New RING Tossed into an Old HAT
p300 and CBP are multi-domain histone acetyltransferases (HATs) that regulate gene expression and are mutated in human diseases including cancer. In the August issue of NSMB, Delvecchio and colleagues report the structure of the p300 catalytic core, revealing the presence of a previously unknown RIN...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836368/ https://ncbi.nlm.nih.gov/pubmed/24010705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.011 |
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