Menadione-Induced DNA Damage Leads to Mitochondrial Dysfunction and Fragmentation During Rosette Formation in Fuchs Endothelial Corneal Dystrophy

Aims: Fuchs endothelial corneal dystrophy (FECD), a leading cause of age-related corneal edema requiring transplantation, is characterized by rosette formation of corneal endothelium with ensuing apoptosis. We sought to determine whether excess of mitochondrial reactive oxygen species leads to chron...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Antioxid Redox Signal
Hoofdauteurs: Halilovic, Adna, Schmedt, Thore, Benischke, Anne-Sophie, Hamill, Cecily, Chen, Yuming, Santos, Janine Hertzog, Jurkunas, Ula V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2016
Onderwerpen:
Original Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931310/
https://ncbi.nlm.nih.gov/pubmed/26935406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6532
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items