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Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

While the oxygen-dependent reversal of lysine N(ɛ)-methylation is well established, the existence of bona fide N(ω)-methylarginine demethylases (RDMs) is controversial. Lysine demethylation, as catalysed by two families of lysine demethylases (the flavin-dependent KDM1 enzymes and the 2-oxoglutarate...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Walport, Louise J., Hopkinson, Richard J., Chowdhury, Rasheduzzaman, Schiller, Rachel, Ge, Wei, Kawamura, Akane, Schofield, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931022/
https://ncbi.nlm.nih.gov/pubmed/27337104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11974
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