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Inhibitors of both the N-methyl lysyl- and arginyl-demethylase activities of the JmjC oxygenases
The Jumonji C (JmjC) family of 2-oxoglutarate (2OG)-dependent oxygenases have established roles in the regulation of transcription via the catalysis of demethylation of Nε-methylated lysine residues in histone tails, especially the N-terminal tail of histone H3. Most human JmjC N(ɛ)-methyl lysine de...
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| Vydáno v: | Philos Trans R Soc Lond B Biol Sci |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Royal Society
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915715/ https://ncbi.nlm.nih.gov/pubmed/29685975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0071 |
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