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Synthesis of β-substituted tryptamines by regioselective ring opening of aziridines
Functionalized tryptamines are targets of interest for development as small molecule therapeutics. The ring opening of aziridines with indoles is a powerful method for tryptamine synthesis if site selectivity can be controlled. 4-Nitrobenzyl carbamate (PNZ)-protected aziridines undergo regioselectiv...
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| Veröffentlicht in: | Tetrahedron |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930112/ https://ncbi.nlm.nih.gov/pubmed/27378819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2016.03.031 |
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