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Regioselective Synthesis of N-β-Hydroxyethylaziridines by the Ring Opening Reaction of Epoxides with Aziridine Generated In Situ
[Image: see text] Biologically important N-β-hydroxyethylaziridine intermediates were conveniently prepared by regioselective ring opening reactions of diversely substituted epoxides. Ethyleneimine generated in situ under basic conditions from β-chloroethylamine was used as a nucleophile to open the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597441/ https://ncbi.nlm.nih.gov/pubmed/16524274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0529703 |
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