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Regioselective Synthesis of N-β-Hydroxyethylaziridines by the Ring Opening Reaction of Epoxides with Aziridine Generated In Situ

[Image: see text] Biologically important N-β-hydroxyethylaziridine intermediates were conveniently prepared by regioselective ring opening reactions of diversely substituted epoxides. Ethyleneimine generated in situ under basic conditions from β-chloroethylamine was used as a nucleophile to open the...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Kim, Ha Young, Talukdar, Arindam, Cushman, Mark
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597441/
https://ncbi.nlm.nih.gov/pubmed/16524274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0529703
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