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Synthesis and ring openings of cinnamate-derived N-unfunctionalised aziridines

tert-Butyl cinnamates are aziridinated with high trans-selectivity by an N–N ylide generated in situ from N-methylmorpholine and O-diphenylphosphinyl hydroxylamine. The resulting N-unfunctionalised aziridines are shown to be versatile synthetic building blocks that undergo highly selective ring-open...

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Detalhes bibliográficos
Main Authors: Armstrong, Alan, Ferguson, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511008/
https://ncbi.nlm.nih.gov/pubmed/23209508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.199
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