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Efficient Regioselective Ring Opening of Activated Aziridine-2-Carboxylates with [(18)F]Fluoride

Aziridines can undergo a range of ring-opening reactions with nucleophiles. The regio- and stereochemistry of the products depend on the substituents on the aziridine. Aziridine ring-opening reactions have rarely been used in radiosynthesis. Herein we report the ring opening of activated aziridine-2...

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Publicat a:ChemistryOpen
Autors principals: Schjoeth-Eskesen, Christina, Hansen, Paul Robert, Kjaer, Andreas, Gillings, Nic
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380955/
https://ncbi.nlm.nih.gov/pubmed/25861572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402081
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