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Photochemical Generation of a Tryptophan Radical within the Subunit Interface of Ribonucleotide Reductase

The E. coli class Ia ribonucleotide reductase (RNR) achieves forward and reverse proton-coupled electron transfer (PCET) over a pathway of redox-active amino acids (β-Y(122) ⇌ β-Y(356) ⇌ α-Y(731) ⇌ α-Y(730) ⇌ α-C(439)) spanning ~35 Å and two subunits every time it turns over. We have developed photo...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Olshansky, Lisa, Greene, Brandon L., Finkbeiner, Chelsea, Stubbe, JoAnne, Nocera, Daniel G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929995/
https://ncbi.nlm.nih.gov/pubmed/27159163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00292
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