Defective association of the platelet glycoprotein Ib-IX complex with the glycosphingolipid-enriched membrane domain inhibits murine thrombus and atheroma formation

Localization of the platelet glycoprotein Ib-IX complex to the membrane lipid domain is essential for platelet adhesion to von Willebrand factor (vWf) and subsequent platelet activation in vitro. Yet, the in vivo importance of this localization has never been addressed. We recently found that the di...

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Veröffentlicht in:J Immunol
Hauptverfasser: Zhou, Hao, Ran, Yali, Da, Qi, Shaw, Tanner S., Shang, Dan, Reddy, Anilkumar K., López, José A., Ballantyne, Christie M., Ware, Jerry, Wu, Huaizhu, Peng, Yuandong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929148/
https://ncbi.nlm.nih.gov/pubmed/27206768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501946
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