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Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib‐IX complex clustering and signaling

Platelet glycoprotein Ib‐IX complex is affixed to the membrane skeleton through interaction with actin binding protein 280 (ABP‐280). We find that removal of the ABP‐280 binding sites in GP Ibα cytoplasmic tail has little impact on the complex clustering induced by antibody crosslinking. However, la...

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Detalhes bibliográficos
Publicado no:IUBMB Life
Main Authors: Shang, Dan, Zhang, Zuping, Wang, Qian, Ran, Yali, Shaw, Tanner S., Van, John N., Peng, Yuandong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132009/
https://ncbi.nlm.nih.gov/pubmed/27634617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1559
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