Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib‐IX complex clustering and signaling

Platelet glycoprotein Ib‐IX complex is affixed to the membrane skeleton through interaction with actin binding protein 280 (ABP‐280). We find that removal of the ABP‐280 binding sites in GP Ibα cytoplasmic tail has little impact on the complex clustering induced by antibody crosslinking. However, la...

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Библиографические подробности
Опубликовано в: :IUBMB Life
Главные авторы: Shang, Dan, Zhang, Zuping, Wang, Qian, Ran, Yali, Shaw, Tanner S., Van, John N., Peng, Yuandong
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132009/
https://ncbi.nlm.nih.gov/pubmed/27634617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1559
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