Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib‐IX complex clustering and signaling

Platelet glycoprotein Ib‐IX complex is affixed to the membrane skeleton through interaction with actin binding protein 280 (ABP‐280). We find that removal of the ABP‐280 binding sites in GP Ibα cytoplasmic tail has little impact on the complex clustering induced by antibody crosslinking. However, la...

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Bibliographic Details
Published in:IUBMB Life
Main Authors: Shang, Dan, Zhang, Zuping, Wang, Qian, Ran, Yali, Shaw, Tanner S., Van, John N., Peng, Yuandong
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132009/
https://ncbi.nlm.nih.gov/pubmed/27634617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1559
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