Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib‐IX complex clustering and signaling

Platelet glycoprotein Ib‐IX complex is affixed to the membrane skeleton through interaction with actin binding protein 280 (ABP‐280). We find that removal of the ABP‐280 binding sites in GP Ibα cytoplasmic tail has little impact on the complex clustering induced by antibody crosslinking. However, la...

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Enregistré dans:
Détails bibliographiques
Publié dans:IUBMB Life
Auteurs principaux: Shang, Dan, Zhang, Zuping, Wang, Qian, Ran, Yali, Shaw, Tanner S., Van, John N., Peng, Yuandong
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132009/
https://ncbi.nlm.nih.gov/pubmed/27634617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1559
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