The Transmembrane Domains of β and IX Subunits Mediate the Localization of the Platelet Glycoprotein Ib-IX Complex to the Glycosphingolipid-enriched Membrane Domain

We have previously reported that the structural elements of the GP Ib-IX complex required for its localization to glycosphingolipid-enriched membranes (GEMs) reside in the Ibβ and IX subunits. To identify them, we generated a series of cell lines expressing mutant GP Ibβ and GP IX where 1) the cytop...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Xu, Guofeng, Shang, Dan, Zhang, Zuping, Shaw, Tanner S., Ran, Yali, López, José A., Peng, Yuandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571966/
https://ncbi.nlm.nih.gov/pubmed/26203189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.668145
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