Defective association of the platelet glycoprotein Ib-IX complex with the glycosphingolipid-enriched membrane domain inhibits murine thrombus and atheroma formation

Localization of the platelet glycoprotein Ib-IX complex to the membrane lipid domain is essential for platelet adhesion to von Willebrand factor (vWf) and subsequent platelet activation in vitro. Yet, the in vivo importance of this localization has never been addressed. We recently found that the di...

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Vydáno v:J Immunol
Hlavní autoři: Zhou, Hao, Ran, Yali, Da, Qi, Shaw, Tanner S., Shang, Dan, Reddy, Anilkumar K., López, José A., Ballantyne, Christie M., Ware, Jerry, Wu, Huaizhu, Peng, Yuandong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929148/
https://ncbi.nlm.nih.gov/pubmed/27206768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501946
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