Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation

OBJECTIVE: The platelet glycoprotein (GP) Ib-IX receptor is a well characterized adhesion receptor supporting hemostasis and thrombosis via interactions with von Willebrand factor (VWF). We examine the GPIb-IX/VWF axis in murine polymicrobial sepsis, as modeled by cecal ligation and puncture (CLP)....

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Bibliographic Details
Main Authors: Corken, Adam, Russell, Susan, Dent, Judith, Post, Steven R., Ware, Jerry
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991762/
https://ncbi.nlm.nih.gov/pubmed/24504734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.303113
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