Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is one of the most common lethal genetic diseases worldwide, caused by mutations in the dystrophin (DMD) gene. Exon skipping employs short DNA/RNA-like molecules called antisense oligonucleotides (AONs) that restore the reading frame and produce shorter but function...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Miskew Nichols, Bailey, Aoki, Yoshitsugu, Kuraoka, Mutsuki, Lee, Joshua J.A., Takeda, Shin'ichi, Yokota, Toshifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927712/
https://ncbi.nlm.nih.gov/pubmed/27285612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53776
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky