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Antisense Oligo-Mediated Multiple Exon Skipping in a Dog Model of Duchenne Muscular Dystrophy

Exon skipping is currently one of the most promising molecular therapies for Duchenne muscular dystrophy (DMD). We have recently developed multiple exon skipping targeting exons 6 and 8 in dystrophin mRNA of canine X-linked muscular dystrophy (CXMD), an animal model of DMD, which exhibits severe dys...

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Publicat a:Methods Mol Biol
Autors principals: Yokota, Toshifumi, Hoffman, Eric, Takeda, Shin’ichi
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491489/
https://ncbi.nlm.nih.gov/pubmed/21194037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61737-982-6_20
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