Development of Multiexon Skipping Antisense Oligonucleotide Therapy for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is an incurable, X-linked progressive muscle degenerative disorder that results from the absence of dystrophin protein and leads to premature death in affected individuals due to respiratory and/or cardiac failure typically by age of 30. Very recently the exciting p...

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Hlavní autoři: Aoki, Yoshitsugu, Yokota, Toshifumi, Wood, Matthew J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747431/
https://ncbi.nlm.nih.gov/pubmed/23984357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/402369
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