Sigma-1 Agonist Binding in the Aging Rat Brain: a MicroPET Study with [(11)C]SA4503

PURPOSE: Sigma-1 receptor ligands modulate the release of several neurotransmitters and intracellular calcium signaling. We examined the binding of a radiolabeled sigma-1 agonist in the aging rat brain with positron emission tomography (PET). PROCEDURES: Time-dependent uptake of [(11)C]SA4503 was me...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Imaging Biol
Prif Awduron: Ramakrishnan, Nisha K., Visser, Anniek K. D., Rybczynska, Anna A., Nyakas, Csaba J., Luiten, Paul G. M., Kwizera, Chantal, Sijbesma, Jurgen W. A., Elsinga, Philip H., Ishiwata, Kiichi, Dierckx, Rudi A. J. O., van Waarde, Aren
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927617/
https://ncbi.nlm.nih.gov/pubmed/26637208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-015-0917-6
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