Sigma-1 Agonist Binding in the Aging Rat Brain: a MicroPET Study with [(11)C]SA4503

PURPOSE: Sigma-1 receptor ligands modulate the release of several neurotransmitters and intracellular calcium signaling. We examined the binding of a radiolabeled sigma-1 agonist in the aging rat brain with positron emission tomography (PET). PROCEDURES: Time-dependent uptake of [(11)C]SA4503 was me...

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Detaylı Bibliyografya
Yayımlandı:Mol Imaging Biol
Asıl Yazarlar: Ramakrishnan, Nisha K., Visser, Anniek K. D., Rybczynska, Anna A., Nyakas, Csaba J., Luiten, Paul G. M., Kwizera, Chantal, Sijbesma, Jurgen W. A., Elsinga, Philip H., Ishiwata, Kiichi, Dierckx, Rudi A. J. O., van Waarde, Aren
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927617/
https://ncbi.nlm.nih.gov/pubmed/26637208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-015-0917-6
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