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Steroid hormones affect binding of the sigma ligand (11)C-SA4503 in tumour cells and tumour-bearing rats

PURPOSE: Sigma receptors are implicated in memory and cognitive functions, drug addiction, depression and schizophrenia. In addition, sigma receptors are strongly overexpressed in many tumours. Although the natural ligands are still unknown, steroid hormones are potential candidates. Here, we examin...

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Main Authors: Rybczynska, Anna A., Elsinga, Philip H., Sijbesma, Jurgen W., Ishiwata, Kiichi, de Jong, Johan R., de Vries, Erik F., Dierckx, Rudi A., van Waarde, Aren
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691528/
https://ncbi.nlm.nih.gov/pubmed/19247652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1076-2
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