Steroid hormones affect binding of the sigma ligand (11)C-SA4503 in tumour cells and tumour-bearing rats

PURPOSE: Sigma receptors are implicated in memory and cognitive functions, drug addiction, depression and schizophrenia. In addition, sigma receptors are strongly overexpressed in many tumours. Although the natural ligands are still unknown, steroid hormones are potential candidates. Here, we examin...

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Hlavní autoři: Rybczynska, Anna A., Elsinga, Philip H., Sijbesma, Jurgen W., Ishiwata, Kiichi, de Jong, Johan R., de Vries, Erik F., Dierckx, Rudi A., van Waarde, Aren
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691528/
https://ncbi.nlm.nih.gov/pubmed/19247652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1076-2
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