Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet–Induced Kidney Disease

Obesity, an important risk factor for metabolic syndrome (MetS) and cardiovascular disease, is often complicated by CKD, which further increases cardiovascular risk and causes ESRD. To elucidate the mechanism underlying this relationship, we investigated the role of the endocytic receptor megalin in...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Kuwahara, Shoji, Hosojima, Michihiro, Kaneko, Reika, Aoki, Hiroyuki, Nakano, Daisuke, Sasagawa, Taiji, Kabasawa, Hideyuki, Kaseda, Ryohei, Yasukawa, Ryota, Ishikawa, Tomomi, Suzuki, Akiyo, Sato, Hiroyoshi, Kageyama, Shun, Tanaka, Takahiro, Kitamura, Nobutaka, Narita, Ichiei, Komatsu, Masaaki, Nishiyama, Akira, Saito, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2016
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926965/
https://ncbi.nlm.nih.gov/pubmed/26534923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020190
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