Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet–Induced Kidney Disease

Obesity, an important risk factor for metabolic syndrome (MetS) and cardiovascular disease, is often complicated by CKD, which further increases cardiovascular risk and causes ESRD. To elucidate the mechanism underlying this relationship, we investigated the role of the endocytic receptor megalin in...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kuwahara, Shoji, Hosojima, Michihiro, Kaneko, Reika, Aoki, Hiroyuki, Nakano, Daisuke, Sasagawa, Taiji, Kabasawa, Hideyuki, Kaseda, Ryohei, Yasukawa, Ryota, Ishikawa, Tomomi, Suzuki, Akiyo, Sato, Hiroyoshi, Kageyama, Shun, Tanaka, Takahiro, Kitamura, Nobutaka, Narita, Ichiei, Komatsu, Masaaki, Nishiyama, Akira, Saito, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926965/
https://ncbi.nlm.nih.gov/pubmed/26534923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020190
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