Significance of Urinary Full-Length and Ectodomain Forms of Megalin in Patients With Type 2 Diabetes

OBJECTIVE: Megalin, an endocytic receptor in proximal tubule cells, is involved in the mechanisms of albuminuria in diabetic nephropathy (DN). To develop efficient novel biomarkers associated with the pathogenesis of DN, we investigated urinary megalin excretion in type 2 diabetes. RESEARCH DESIGN A...

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Detalhes bibliográficos
Main Authors: Ogasawara, Shinya, Hosojima, Michihiro, Kaseda, Ryohei, Kabasawa, Hideyuki, Yamamoto-Kabasawa, Keiko, Kurosawa, Hiroyuki, Sato, Hiroyoshi, Iino, Noriaki, Takeda, Tetsuro, Suzuki, Yoshiki, Narita, Ichiei, Yamagata, Kunihiro, Tomino, Yasuhiko, Gejyo, Fumitake, Hirayama, Yoshiaki, Sekine, Sakari, Saito, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329833/
https://ncbi.nlm.nih.gov/pubmed/22410816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-1684
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