Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet–Induced Kidney Disease

Obesity, an important risk factor for metabolic syndrome (MetS) and cardiovascular disease, is often complicated by CKD, which further increases cardiovascular risk and causes ESRD. To elucidate the mechanism underlying this relationship, we investigated the role of the endocytic receptor megalin in...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Kuwahara, Shoji, Hosojima, Michihiro, Kaneko, Reika, Aoki, Hiroyuki, Nakano, Daisuke, Sasagawa, Taiji, Kabasawa, Hideyuki, Kaseda, Ryohei, Yasukawa, Ryota, Ishikawa, Tomomi, Suzuki, Akiyo, Sato, Hiroyoshi, Kageyama, Shun, Tanaka, Takahiro, Kitamura, Nobutaka, Narita, Ichiei, Komatsu, Masaaki, Nishiyama, Akira, Saito, Akihiko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926965/
https://ncbi.nlm.nih.gov/pubmed/26534923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020190
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