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Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival

As a critical regulator of cell growth, the mechanistic target of rapamycin (mTOR) protein operates as part of two molecularly and functionally distinct complexes. Herein, we demonstrate that mTOR complex molecular composition varies in different somatic tissues. In astrocytes and neural stem cells,...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Smithson, Laura J., Gutmann, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926861/
https://ncbi.nlm.nih.gov/pubmed/27340174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279661.116
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