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Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival
As a critical regulator of cell growth, the mechanistic target of rapamycin (mTOR) protein operates as part of two molecularly and functionally distinct complexes. Herein, we demonstrate that mTOR complex molecular composition varies in different somatic tissues. In astrocytes and neural stem cells,...
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| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4926861/ https://ncbi.nlm.nih.gov/pubmed/27340174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279661.116 |
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