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v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage

An increase in Src activity is commonly observed in epithelial cancers. Aberrant activation of the kinase activity is associated with malignant progression. However, the mechanisms that underlie the Src-induced malignant progression of cancer are not completely understood. We show here that v-Src, a...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Ikeuchi, Masayoshi, Fukumoto, Yasunori, Honda, Takuya, Kuga, Takahisa, Saito, Youhei, Yamaguchi, Naoto, Nakayama, Yuji
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926405/
https://ncbi.nlm.nih.gov/pubmed/27271602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060871
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