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v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage

An increase in Src activity is commonly observed in epithelial cancers. Aberrant activation of the kinase activity is associated with malignant progression. However, the mechanisms that underlie the Src-induced malignant progression of cancer are not completely understood. We show here that v-Src, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Ikeuchi, Masayoshi, Fukumoto, Yasunori, Honda, Takuya, Kuga, Takahisa, Saito, Youhei, Yamaguchi, Naoto, Nakayama, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926405/
https://ncbi.nlm.nih.gov/pubmed/27271602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060871
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