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Targeted Gene Knockin in Porcine Somatic Cells Using CRISPR/Cas Ribonucleoproteins

The pig is an ideal large animal model for genetic engineering applications. A relatively short gestation interval and large litter size makes the pig a conducive model for generating and propagating genetic modifications. The domestic pig also shares close similarity in anatomy, physiology, size, a...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Park, Ki-Eun, Park, Chi-Hun, Powell, Anne, Martin, Jessica, Donovan, David M., Telugu, Bhanu P.
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926344/
https://ncbi.nlm.nih.gov/pubmed/27240344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060810
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