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Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes

The domestic pig is an important “dual purpose” animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. Howeve...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Park, Ki-Eun, Powell, Anne, Sandmaier, Shelley E. S., Kim, Chan-Mi, Mileham, Alan, Donovan, David M., Telugu, Bhanu P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307959/
https://ncbi.nlm.nih.gov/pubmed/28195163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42458
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