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Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes

The domestic pig is an important “dual purpose” animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. Howeve...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Park, Ki-Eun, Powell, Anne, Sandmaier, Shelley E. S., Kim, Chan-Mi, Mileham, Alan, Donovan, David M., Telugu, Bhanu P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307959/
https://ncbi.nlm.nih.gov/pubmed/28195163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42458
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