Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene

Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model of human physiology and an agriculturally important species. In this study, we utilized the CRISPR/Cas9 system to edit the NANOS2 gene in pig...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Ki-Eun, Kaucher, Amy V., Powell, Anne, Waqas, Muhammad Salman, Sandmaier, Shelley E.S., Oatley, Melissa J., Park, Chi-Hun, Tibary, Ahmed, Donovan, David M., Blomberg, Le Ann, Lillico, Simon G., Whitelaw, C. Bruce A., Mileham, Alan, Telugu, Bhanu P., Oatley, Jon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223215/
https://ncbi.nlm.nih.gov/pubmed/28071690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40176
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