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Somatic Cell Nuclear Transfer Followed by CRIPSR/Cas9 Microinjection Results in Highly Efficient Genome Editing in Cloned Pigs

The domestic pig is an ideal “dual purpose” animal model for agricultural and biomedical research. With the availability of genome editing tools such as clustered regularly interspaced short palindromic repeat (CRISPR) and associated nuclease Cas9 (CRISPR/Cas9), it is now possible to perform site-sp...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Sheets, Timothy P., Park, Chi-Hun, Park, Ki-Eun, Powell, Anne, Donovan, David M., Telugu, Bhanu P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187831/
https://ncbi.nlm.nih.gov/pubmed/27918485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17122031
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