Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn “On” Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model

Lignende værker

• Marmosets as a preclinical model for testing “off-label” use of doxycycline to turn on Flt3L expression from high-capacity adenovirus vectors
  af: VanderVeen, Nathan, et al.
  Udgivet: (2014)
• Effectiveness and Preclinical Safety Profile of Doxycycline to Be Used “Off-Label” to Induce Therapeutic Transgene Expression in a Phase I Clinical Trial for Glioma
  af: VanderVeen, Nathan, et al.
  Udgivet: (2013)
• Effective High-Capacity Gutless Adenoviral Vectors Mediate Transgene Expression in Human Glioma Cells
  af: Candolfi, Marianela, et al.
  Udgivet: (2006)
• Optimization of adenoviral vector–mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro
  af: Candolfi, Marianela, et al.
  Udgivet: (2007)
• Immunization Against the Transgene but not the TetON Switch Reduces Expression From Gutless Adenoviral Vectors in the Brain
  af: Xiong, Weidong, et al.
  Udgivet: (2008)