Marmosets as a preclinical model for testing “off-label” use of doxycycline to turn on Flt3L expression from high-capacity adenovirus vectors

We developed a combined conditional cytotoxic, i.e., herpes simplex type 1-thymidine kinase (TK), plus immune-stimulatory, i.e., fms-like tyrosine kinase ligand-3–mediated gene therapy for glioblastoma multiforme (GBM). Therapeutic transgenes were encoded within high-capacity adenoviral vectors (HC-...

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Detalhes bibliográficos
Main Authors: VanderVeen, Nathan, Paran, Christopher, Appelhans, Ashley, Krasinkiewicz, Johnny, Lemons, Rosemary, Appelman, Henry, Doherty, Robert, Palmer, Donna, Ng, Philip, Lowenstein, Pedro R, Castro, Maria G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111110/
https://ncbi.nlm.nih.gov/pubmed/25068145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2013.10
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