Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Human babesiosis is a tick-borne multisystem disease caused by Babesia species of the apicomplexan phylum. Most clinical cases and fatalities of babesiosis are caused by Babesia microti. Current treatment for human babesiosis consists of two drug combinations, atovaquone + azithromycin or quinine +...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Lawres, Lauren A., Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P., Renard, Isaline, Virji, Azan Z., Boulard, Pierre, Rodriguez, Eduardo X., Allen, Alexander J., Pou, Sovitj, Wegmann, Keith W., Winter, Rolf W., Nilsen, Aaron, Mao, Jialing, Preston, Douglas A., Belperron, Alexia A., Bockenstedt, Linda K., Hinrichs, David J., Riscoe, Michael K., Doggett, J. Stone, Ben Mamoun, Choukri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2016
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925016/
https://ncbi.nlm.nih.gov/pubmed/27270894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151519
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