Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Human babesiosis is a tick-borne multisystem disease caused by Babesia species of the apicomplexan phylum. Most clinical cases and fatalities of babesiosis are caused by Babesia microti. Current treatment for human babesiosis consists of two drug combinations, atovaquone + azithromycin or quinine +...

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發表在:J Exp Med
Main Authors: Lawres, Lauren A., Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P., Renard, Isaline, Virji, Azan Z., Boulard, Pierre, Rodriguez, Eduardo X., Allen, Alexander J., Pou, Sovitj, Wegmann, Keith W., Winter, Rolf W., Nilsen, Aaron, Mao, Jialing, Preston, Douglas A., Belperron, Alexia A., Bockenstedt, Linda K., Hinrichs, David J., Riscoe, Michael K., Doggett, J. Stone, Ben Mamoun, Choukri
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2016
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925016/
https://ncbi.nlm.nih.gov/pubmed/27270894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151519
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