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Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment

Tumor-homing peptides with tissue-penetrating properties increase the efficacy of targeted cancer therapy by delivering an anticancer agent to the tumor interior. LyP-1 (CGNKRTRGC) and iRGD (CRGDKGPDC) are founding members of this class of peptides. The presence of the cysteines forming the cyclizin...

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Publicat a:Breast Cancer (Auckl)
Autors principals: Kotamraju, Venkata Ramana, Sharma, Shweta, Kolhar, Poornima, Agemy, Lilach, Pavlovich, James, Ruoslahti, Erkki
Format: Artigo
Idioma:Inglês
Publicat: Libertas Academica 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924884/
https://ncbi.nlm.nih.gov/pubmed/27385913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BCBCR.S29426
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