UROKINASE-CONTROLLED TUMOR PENETRATING PEPTIDE

Tumor penetrating peptides contain a cryptic (R/K)XX(R/K) CendR element that must be C-terminally exposed to trigger neuropilin-1 (NRP-1) binding, cellular internalization and malignant tissue penetration. The specific proteases that are involved in processing of phage display identified tumor penet...

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Bibliographic Details
Published in:J Control Release
Main Authors: Braun, Gary B., Sugahara, Kazuki N., Yu, Olivia M., Kotamraju, Venkata Ramana, Mölder, Tarmo, Lowy, Andrew M., Ruoslahti, Erkki, Teesalu, Tambet
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359125/
https://ncbi.nlm.nih.gov/pubmed/27106816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.04.027
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