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UROKINASE-CONTROLLED TUMOR PENETRATING PEPTIDE
Tumor penetrating peptides contain a cryptic (R/K)XX(R/K) CendR element that must be C-terminally exposed to trigger neuropilin-1 (NRP-1) binding, cellular internalization and malignant tissue penetration. The specific proteases that are involved in processing of phage display identified tumor penet...
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| Pubblicato in: | J Control Release |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359125/ https://ncbi.nlm.nih.gov/pubmed/27106816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.04.027 |
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