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Co-administration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

Poor penetration of anti-cancer drugs into tumors can be an important factor limiting their efficacy. Studying mouse tumor models, we show that a previously characterized tumor-penetrating peptide, iRGD (CRGDK/RGPD/EC), increased vascular and tissue permeability in a tumor-specific and neuropilin-1-...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sugahara, Kazuki N., Teesalu, Tambet, Karmali, Priya Prakash, Kotamraju, Venkata Ramana, Agemy, Lilach, Greenwald, Daniel R., Ruoslahti, Erkki
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881692/
https://ncbi.nlm.nih.gov/pubmed/20378772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1183057
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