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Co-administration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs
Poor penetration of anti-cancer drugs into tumors can be an important factor limiting their efficacy. Studying mouse tumor models, we show that a previously characterized tumor-penetrating peptide, iRGD (CRGDK/RGPD/EC), increased vascular and tissue permeability in a tumor-specific and neuropilin-1-...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881692/ https://ncbi.nlm.nih.gov/pubmed/20378772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1183057 |
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