Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody

Broadly neutralizing antibodies targeting the stalk region of influenza A virus (IAV) hemagglutinin (HA) are effective in blocking virus infection both in vitro and in vivo. The highly conserved epitopes recognized by these antibodies are critical for the membrane fusion function of HA and therefore...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chai, Ning, Swem, Lee R., Reichelt, Mike, Chen-Harris, Haiyin, Luis, Elizabeth, Park, Summer, Fouts, Ashley, Lupardus, Patrick, Wu, Thomas D., Li, Olga, McBride, Jacqueline, Lawrence, Michael, Xu, Min, Tan, Man-Wah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924800/
https://ncbi.nlm.nih.gov/pubmed/27351973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005702
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