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Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

Endometrial carcinoma is the most prevalent gynecologic cancer in the United States. The tumor suppressor gene Pten (phosphatase and tensin homolog) is commonly mutated in the more common type 1 (endometrioid) subtype. The glucose-regulated protein 94 (GRP94) is emerging as a novel regulator for can...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shen, Jieli, Yao, Lijing, Lin, Yvonne G., DeMayo, Francesco J., Lydon, John P., Dubeau, Louis, Lee, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924759/
https://ncbi.nlm.nih.gov/pubmed/26910913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7450
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