Pten and Dicer1 loss in the mouse uterus causes poorly-differentiated endometrial adenocarcinoma

Endometrial cancer remains the most common gynecological malignancy in the United States. While the loss of the tumor suppressor, PTEN (phosphatase and tensin homolog), is well studied in endometrial cancer, recent studies suggest that DICER1, the endoribonuclease responsible for miRNA genesis, also...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Wang, Xiyin, Wendel, Jillian R. H., Emerson, Robert E., Broaddus, Russell R., Creighton, Chad J., Rusch, Douglas B., Buechlein, Aaron, DeMayo, Francesco J., Lydon, John P., Hawkins, Shannon M.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541676/
https://ncbi.nlm.nih.gov/pubmed/32843721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01434-5
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