Pten and Dicer1 loss in the mouse uterus causes poorly-differentiated endometrial adenocarcinoma

Endometrial cancer remains the most common gynecological malignancy in the United States. While the loss of the tumor suppressor, PTEN (phosphatase and tensin homolog), is well studied in endometrial cancer, recent studies suggest that DICER1, the endoribonuclease responsible for miRNA genesis, also...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Xiyin, Wendel, Jillian R. H., Emerson, Robert E., Broaddus, Russell R., Creighton, Chad J., Rusch, Douglas B., Buechlein, Aaron, DeMayo, Francesco J., Lydon, John P., Hawkins, Shannon M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541676/
https://ncbi.nlm.nih.gov/pubmed/32843721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01434-5
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